Animalscaretips
- When was C. elegans discovered?
- Who developed C. elegans as a model organism?
- Why is C. elegans famous?
- Can elegans reproduce?
- What is Evo Devo research?
- Who named C. elegans?
- Why is Mus musculus a good model organism?
- How much DNA do we share with C. elegans?
- Why are zebrafish model organisms?
- Can you see C. elegans with the naked eye?
- Can C. elegans infect humans?
- What is AC elegan?
- Can hermaphrodites self fertilize?
- How long do C. elegans live?
When was C. elegans discovered?
The nematode worm Caenorhabditis elegans was first studied in the laboratory by Victor Nigon and Ellsworth Dougherty in the 1940s, but came to prominence after being adopted by Sydney Brenner in 1963 as a model organism for the study of developmental biology using genetics.
Who developed C. elegans as a model organism?
After initial work by Emile Maupas (Maupas, 1900) and Victor Nigon (Nigon, 1949; Nigon et al., 1960) on its mode of reproduction, meiosis and development, experiments by Sydney Brenner and collaborators in the 1960s and 1970s raised C. elegans to the status of a premier model organism.
Why is C. elegans famous?
Many of the genes in the C. elegans genome have functional counterparts in humans which makes it an extremely useful model for human diseases. C. elegans mutants provide models for many human diseases including neurological? disorders, congenital heart disease and kidney disease.
Can elegans reproduce?
elegans can reproduce either by self-fertilization or by mating with males. A self-fertilizing hermaphrodite can produce around 300 offspring before sperm depletion; an outcrossed hermaphrodite supplied with plentiful virile males can produce as many as 1,400 offspring.
What is Evo Devo research?
Evolutionary developmental biology (informally, evo-devo) is a field of biological research that compares the developmental processes of different organisms to infer the ancestral relationships between them and how developmental processes evolved.
Who named C. elegans?
A key figure of this phase is Emile Maupas, a professional archivist and librarian living in Algiers and working on biology as a personal interest (see Appendix 3, Section 18.1). He was the first to isolate and name Rhabditis elegans (now Caenorhabditis elegans) (Maupas, 1900).
Why is Mus musculus a good model organism?
musculus is often used as a preferred model organism due to the similarity with the human genome of 85% and genome size ~2.5 Gbp. Despite being bigger than the other model organisms discussed in this series, mice are still relatively easily to care for, breed and study.
How much DNA do we share with C. elegans?
The homology between human CGI genes and C. elegans genes is approximately 41% (20% to 71% in range) and similarity is even more striking at 59% (34% to 87%), as shown in Fig.
Why are zebrafish model organisms?
Zebrafish embryos are nearly transparent which allows researchers to easily examine the development of internal structures. ... As zebrafish eggs are fertilised and develop outside the mother's body it is an ideal model organism for studying early development. Zebrafish have a similar genetic structure to humans.
Can you see C. elegans with the naked eye?
Caenorhabditis elegans is a free-living (non-parasitic) worm approximately 1 mm long. They are visible to the naked eye but we use microscopes to visualize them better—both the embryo and adult are transparent.
Can C. elegans infect humans?
elegans [8-16]. Pseudomonas aeruginosa is an opportunistic bacterial pathogen of humans and the most commonly studied pathogen in C. elegans, where it causes a lethal infection of intestinal epithelial cells [17].
What is AC elegan?
AN INTRODUCTION FOR THOSE UNFAMILIAR WITH “THE WORM”. C. elegans is a nematode—a member of the phylum Nematoda: ... The roundworms and threadworms, a phylum of smooth-skinned, unsegmented worms with a long cylindrical body shape tapered at the ends; includes free-living and parasitic forms both aquatic and terrestrial.
Can hermaphrodites self fertilize?
Hermaphroditic animals (those in which both male and female gonads are borne on one individual) are rarely capable of self-fertilization, since many such species have adaptations encouraging cross-fertilization.
How long do C. elegans live?
Adult C. elegans are 1 mm long self-fertilizing hermaphrodites with a 2.5–4 days reproductive cycle at room temperature, and a mean lifespan of approximately 18–20 days when cultured at 20°C (4–7).
