Franklin

What is the significance of Franklin and Wilkins' X-ray diffraction photographs regarding DNA structure?

What is the significance of Franklin and Wilkins' X-ray diffraction photographs regarding DNA structure?

X-ray diffraction photography method was invented by Rosalind Franklin and Maurice Wilkins. This method helped in detecting structures of many microscopic objects. This was the method that helped sir Watson and Crick to detect the structure that is, the double helical model of DNA.

  1. How did Franklin and Wilkins study of X-ray diffraction provide evidence for DNA helix structure?
  2. What role did Wilkins and Franklin play in the structure of DNA?
  3. What was the significance of Rosalind Franklin's work and results?
  4. What did Rosalind Franklin's X-ray crystallography data indicate about the structure of DNA?
  5. What did Franklin and Wilkins discover?
  6. Which is the significance of the pairing of nitrogenous bases?
  7. How did Rosalind Franklin impact the world?
  8. What is Rosalind Franklin best known for?
  9. Why is understanding the structure of DNA important?
  10. What is Rosalind Franklin's legacy?
  11. Was Rosalind Franklin's work stolen?
  12. Why is Xray Diffraction useful?
  13. Was Rosalind Franklin wrong?
  14. What did Wilkins do for DNA?
  15. How did Rosalind Franklin discover DNA?
  16. How Maurice Wilkins contributed to the understanding of DNA?

How did Franklin and Wilkins study of X-ray diffraction provide evidence for DNA helix structure?

At King's College in London, Rosalind Franklin and Maurice Wilkins were studying DNA. Wilkins and Franklin used X-ray diffraction as their main tool -- beaming X-rays through the molecule yielded a shadow picture of the molecule's structure, by how the X-rays bounced off its component parts.

What role did Wilkins and Franklin play in the structure of DNA?

At King's College London, Rosalind Franklin obtained images of DNA using X-ray crystallography, an idea first broached by Maurice Wilkins. Franklin's images allowed James Watson and Francis Crick to create their famous two-strand, or double-helix, model.

What was the significance of Rosalind Franklin's work and results?

Rosalind Franklin discovered the density of DNA and, more importantly, established that the molecule existed in a helical conformation. Her work to make clearer X-ray patterns of DNA molecules laid the foundation for James Watson and Francis Crick's suggestion that DNA is a double-helix polymer in 1953.

What did Rosalind Franklin's X-ray crystallography data indicate about the structure of DNA?

Rosalind Franklin's X-ray diffraction patterns of DNA molecules rendered the important clue that DNA has the structure of a double helix.

What did Franklin and Wilkins discover?

In 1962, James Watson, Francis Crick and Maurice Wilkins received the Nobel prize for the discovery of the structure of DNA. Notably absent from the podium was Rosalind Franklin, whose X-ray photographs of DNA contributed directly to the discovery of the double helix.

Which is the significance of the pairing of nitrogenous bases?

The four different bases pair together in a way known as complementary pairing. Adenine always pairs with thymine, and cytosine always pairs with guanine. The pairing nature of DNA is useful because it allows for easier replication. If you know one side of a DNA molecule, you can always recreate the other side.

How did Rosalind Franklin impact the world?

Her research helped solve the mystery of the structure of DNA - the building blocks of life. ... In 1952, Franklin took X-Ray photographs of a molecule that showed DNA contains two strands wrapped around each other in a double helix, like a twisted ladder.

What is Rosalind Franklin best known for?

She is best known for an X-ray diffraction image that she and her graduate student Raymond Gosling published in 19531, which was key to the determination of the DNA double helix. But Franklin's remarkable work on DNA amounts to a fraction of her record and legacy.

Why is understanding the structure of DNA important?

Understanding the structure and function of DNA has helped revolutionise the investigation of disease pathways, assess an individual's genetic susceptibility to specific diseases, diagnose genetic disorders, and formulate new drugs. It is also critical to the identification of pathogens.

What is Rosalind Franklin's legacy?

Rosalind Franklin's short scientific carrier produced brilliant contributions to the structure of carbon, DNA, and helical and spherical viruses. At 30, she was a recognized authority who switched from carbon to DNA research and, a few years later, to nucleic-acid-protein complexes known as viruses.

Was Rosalind Franklin's work stolen?

Others argue that that Franklin's work was not confidential; Watson and Crick found it in a public setting and did not 'steal' anything from her. One year later, in 1953, Watson and Crick made scientific history by publishing a new model of the DNA code, including the crystallography photograph and Franklin's research.

Why is Xray Diffraction useful?

X-ray diffraction is a powerful nondestructive technique for characterizing crystalline materials. It provides information on structures, phases, preferred crystal orientations (texture), and other structural parameters, such as average grain size, crystallinity, strain, and crystal defects.

Was Rosalind Franklin wrong?

It again airs out the controversy over Franklin's contribution to the work that won the Nobel. ... He also contended that, as Franklin was unaware of any unauthorized sharing of her data with Wilkins, Watson and Crick, and thus did not feel wronged, no wrong-doing occurred.

What did Wilkins do for DNA?

Wilkins is most well-known for beginning the X-ray diffraction images of DNA that contributed to Watson and Crick's discovery of the double-helix structure of DNA.

How did Rosalind Franklin discover DNA?

Studying DNA structure with X-ray diffraction, Franklin and her student Raymond Gosling made an amazing discovery: They took pictures of DNA and discovered that there were two forms of it, a dry "A" form and a wet "B" form. ... "Her photographs were among the most beautiful X-ray photographs of any substance ever taken.

How Maurice Wilkins contributed to the understanding of DNA?

Maurice Wilkins initiated the experimental research into DNA that culminated in Watson and Crick's discovery of its structure in 1953. ... His initial X-ray diffraction work indicated that DNA molecules are helix shaped. He shared the 1962 Nobel Prize in Physiology or Medicine with Francis Crick and James Watson.

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