What are the factors that regulate MSH secretion?

Ultraviolet (UV) rays, increase MSH production by the skin and pituitary gland. It has a vital role in making pigmentation (coloring) of the skin, hair, and eyes. Specialized skin cells known as melanocytes produce melanin, which helps protect cells from skin cancer.

1. How is MSH secretion controlled?
2. What controls the release of MSH?
3. What triggers MSH release?
4. What cell type secretes MSH?
5. What is the target of MSH?
6. What is the target tissue of MSH?
7. What inhibits MSH?
8. Which of the following hormones stimulates secretion of estrogen and sperm production?
9. What is regulated by the hypothalamus?
10. What cells produce alpha MSH?
11. What does pituitary gland control?
12. What stimulates CRH release?
13. What stimulates adrenal medulla?
14. What hormone is produced by Adenohypophysis?
15. What do Corticotrophs produce and release?

How is MSH secretion controlled?

Melanophore stimulating hormone (MSH) secretion from the vertebrate pars intermedia is regulated as for other pituitary hormones, by the hypothalamus. ... A large number of investigators support the view that MSH secretion is regulated by neurotransmitters.

What controls the release of MSH?

How is melanocyte-stimulating hormone controlled? Melanocyte-stimulating hormone secretion from the pituitary is increased by exposure to UV light. Unlike most hormones, melanocyte-stimulating hormone release is not thought to be controlled by a direct feedback mechanism.

What triggers MSH release?

Melanocytes in skin make and secrete MSH in response to ultraviolet light, where it increases synthesis of melanin. Some neurons in arcuate nucleus of the hypothalamus make and secrete α-MSH in response to leptin; α-MSH is also made and secreted in the anterior lobe of the pituitary gland.

What cell type secretes MSH?

Corticotropic cells secrete adrenocorticotropic hormone (ACTH) and melanocyte-stimulating hormone (MSH). Gonadotropic cells secrete follicle stimulating hormone (FSH) and luteinizing hormone (LH).

What is the target of MSH?

The target cells of MSH are melanocytes (melanin-producing cells) and melanophores (melanin-containing cells). MSH stimulates melanocytes to produce melanin and the melanophores to expand, thereby, resulting in the darkening of the skin.

What is the target tissue of MSH?

Following secretion from the pituitary, MSH circulates in the blood and binds to MCRs on the surface of pigment-containing cells called melanocytes (in humans) and chromatophores (in lower vertebrates).

What inhibits MSH?

Cytochalasin B inhibits MSH release even at a high concentration (10%) of dimethylsulfoxide (DMSO) which, itself, is "stimulatory" to hormone release. MSH release in high DMSO concentration is also inhibited by ouabain or by the absence of Ca2+ from the medium.

Which of the following hormones stimulates secretion of estrogen and sperm production?

Luteinizing hormone (LH) and follicle-stimulating hormone (FSH) are called gonadotropins because stimulate the gonads - in males, the testes, and in females, the ovaries.

What is regulated by the hypothalamus?

The hypothalamus is responsible for the regulation of certain metabolic processes and other activities of the autonomic nervous system. ... The hypothalamus controls body temperature, hunger, important aspects of parenting and attachment behaviours, thirst, fatigue, sleep, and circadian rhythms.

What cells produce alpha MSH?

α-MSH is produced by immune cells, by keratinocytes and is also present in the aqueous humour of the eye [132-135].

What does pituitary gland control?

The pituitary gland is called the 'master gland' as the hormones it produces control so many different processes in the body. ... Through secretion of its hormones, the pituitary gland controls metabolism, growth, sexual maturation, reproduction, blood pressure and many other vital physical functions and processes.

What stimulates CRH release?

Stress induces the hypothalamic production and release of CRH, which then causes the activation of the CRH receptor (CRHR) type 1 (CRHR-1) in the anterior pituitary to stimulate ACTH release, as well as proopiomelanocortin (POMC) expression and processing.

What stimulates adrenal medulla?

Stimulation of the adrenal medulla is via preganglionic sympathetic fibers causing release of dopamine, norepinephrine and epinephrine. Sympathetic neural outflow is increased by the fight-or-flight response, fear, emotional stress, upright posture, pain, cold, hypotension, hypoglycemia and other stress.

What hormone is produced by Adenohypophysis?

The cells within this lobe are responsible for the synthesis of at least six major hormones: growth hormone (GH), prolactin (PRL) or luteotropic hormone (LTH) and adrenocorticotropin (ACTH), follicle-stimulating hormone (FSH), luteinizing hormone (LH) and thyroid-stimulating hormone (TSH) or thyrotropin.

What do Corticotrophs produce and release?

Corticotropes produce and release ACTH, a 39 amino acid peptide hormone, in response to corticotropic releasing hormone (CRH) release from the hypothalamus.